A few steps from malaria vaccine

August 29, 2013 – 01:54

The day you will find the malaria vaccine will be a good day for humanity. And maybe that day may have arrived. They are in fact positive results for the first phase of testing of a new malaria vaccine based on a weakened version of the so harmless 'sporozoites', the cells of malarial parasite that develop in the salivary glands of the mosquito vector.

The study, which was conducted by researchers at the National Institute of Allergy and Infectious Diseases (NIAID) and collaborators at the Walter Reed Army Institute of Research and the Naval Medical Research Center covers 57 healthy volunteers who underwent tests to verify the 'effectiveness of the experimental vaccine, developed by scientists and baptized PfSPZ Sanaria Inc., a biotechnology company in Rockville.

Malaria is an infectious disease that still kills in the world about a million deaths per year, most of them in Sub-Saharan Africa. According to estimates by the World Health Organization, in 2010 alone were infected 219 million people. The victims are mostly young people in Africa, for every minute a child dies of malaria.

E 'caused by parasites that are transmitted to humans by mosquitoes. According to estimates, about 40% of the world population lives in areas where malaria is endemic, that is always present among the population of a certain geographical area, with a number of cases substantially constant over time.

For this there is to be happy at the news that a group of researchers may have laid the foundation to eradicate this scourge of humanity.

In the past it was observed that the mosquito bites treated with radiation gradually make it immune to the disease. The problem is that the amount of "pinches" required is too high, at least a thousand. For this, the researchers decided to work directly with the parasites transmitted by mosquitoes. "The next step will be to try to figure out how long the protection lasts over time" - says the study's first author, Robert Seder of the Vaccine Research Center at the National Institutes of Health in Maryland. "The fact" - he continues - "that should be injected directly into a vein rather than subcutaneously as most of the vaccines could make difficult the administration. "

"The global impact of malaria is enormous and unacceptable" - shows Anthony S. Fauci, director of the National Institute of Allergy and Infectious Diseases - "Scientists and health professionals have made ​​significant progress in characterizing, treat and prevent disease, but to get a vaccine remains the goals to be scored. We are encouraged by this important step forward. "

Currently there are 20 vaccines against malaria in the study, some in Phase 1, Phase 2 others and one in phase 3 of the trial. The next step therefore will be to test it on more people to better understand what is the effective dose, and to understand the feasibility of administering it intravenously, a mode is not much used for vaccines.

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Source: www.buonenotizie.it

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Vials of Virus Missing from Army Lab

2009-04-26 15:39:53 by ManOfFewWords

Army criminal investigators are looking into the possibility that disease samples are missing from biolabs at Fort Detrick.
As first reported in today's edition of The Frederick News-Post by columnist Katherine Heerbrandt, the investigators are from the U.S. Army Criminal Investigation Division unit at Fort Meade.
Chad Jones, spokesman for Fort Meade, said CID is investigating the possibility of missing virus samples from the U.S. Army Medical Research Institute of Infectious Diseases.
He said the only other detail he could provide is that the investigation is ongoing

US Army is missing lethal flu vials from lab

2009-04-28 19:35:15 by LetsNotTalkAboutIt

The U.S. Army is finishing an investigation into the disappearance of three vials of a potentially lethal pathogen from the U.S. Army Medical Research Institute of Infectious Diseases at Fort Detrick, Md., the Washington Post reported today (see GSN, Feb. 10).

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