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Inhibition of the JAK-STAT3 pathway by andrographolide enhances

Student Number Author Hsing-hsi Yang (Yang Xing Xi) Author's Email Address No Public. Statistics This thesis had been viewed 368 times. Download 260 times. Department Graduate Institute of Environmental Engineering Year 2011 Semester 2 Degree Master Type of Document Master's Thesis Language zh-TW.Big5 Chinese Title Degradation of Environmental Hormones Alkylphenol in Water by Ozone combined with UV / Hydrogen Peroxide Processes Date of Defense 2012-07-14 Page Count 127 Keyword

  • Alkylphenol
  • Hydrogen peroxide
  • Nonylphenol
  • O3/UV/H2O2
  • Octylphenol
  • Ozone
  • Abstract The process of combining O3 with UV/H2O2 could make serial chemical reactions and produce more active hydroxyl radicals, which have stronger oxidation capacity than conventional oxidants. Consequently, the O3/UV/H2O2 process would be more effective compared to other types of oxidation combination systems. Accordingly, this study evaluates the treatment of alkylphenol aqueous solutions by using the O3/UV/H2O2 process. The effect of various operating parameters including initial pH, H2O2 dosage, initial rate of ozone concentration and initial substrate concentration on the removal of alkylphenols in the O3/UV/H2O2 process was investigated. Moreover, the possible degradation mechanism of alkylphenols in the O3/UV/H2O2 process, bio-toxicity tests (Microtox), and estrogenic activity of reaction aqueous solution were evaluated.
    The results of the investigation show that using the O3/UV/H2O2 process can remove 90% of alkylphenols within 15 minutes, and the reaction time is shorter than other processes. Nevertheless, the mineralization efficiency of alkylphenols in the O3/UV/H2O2 process was only 60%, the results indicated that the alkylphenols only destroyed their own structure and formed numerous intermediate products. However, removal of total organic carbon in solution was ineffective. In order to enhance mineralization of alkylphenols, the oxidation time must be increased.
    The optimum operating conditions for the O3/UV/H2O2 process to destroy alkylphenols found in this study were summarized as follows: UV light intensity = 1.9 × 10-6 Einstein L-1s-1, pH = 4, [O3] = 0.06mg / min, [H2O2] 0 / [AP] 0 molar ratio = 20. In which, the treatment effectiveness of OP and NP were 91.94% and 90.41% after 15 minutes, respectively.
    The degradation products were analyzed by LC / MS, and revealed that the degradation of alkylphenols begins from shortening the alkyl chain. The following may be substitution of the hydrogen on chain with a hydroxyl radical, as well as an additional hydroxyl radical to the aromatic ring . The degradation intermediates are alkylcatechol, 1, 2, 4-trihydroxybenzene, hydroquinone, muconaldehyde, muconic acid, and other small fragments, such as alkanes, acetic acid, carboxylic acids and other compounds.
    With the oxidation time increasing, the bio-toxicity (Microtox) and estrogenic activity of alkylphenols aqueous solution was reduced. However, the results of the investigation show that the intermediate products still had estrogenic activity. The possible causes with the formation of numerous intermediate products to enhance the synergistic effect on the estrogenic activity after alkylphenol degradation, thus, increasing the estrogenic activity of the compounds themselves. Table of Content Summary I
    Abstract II
    Acknowledgements IV
    Contents V
    List of Figures VII
    Table directory X
    Chapter 1 Introduction 1
    Chapter 2 Literature Review 4
    2.1 The definition of environmental hormones and mechanism 4
    2.2 alkylphenols sources and characteristics of the impact on the environment and the flow distribution and control the status of six
    2.3 alkylphenols common way of handling 15
    2.4 Advanced oxidation process 17
    Characteristics 18 2.4.1 Hydrogen Peroxide
    Principle 18 2.4.2 UV oxidation process
    2.4.3 Basic characteristics of ozone oxidation principle 19
    2.5 Ozone combined with UV / hydrogen peroxide process 25
    2.5.1 O3/UV/H2O2 principles and procedural mechanisms affecting factors 25
    2.5.2 O3/UV/H2O2 Apps Status 28
    Chapter 3 Experimental equipment, materials and methods 33
    3.1 Experimental apparatus 33
    3.2 Experimental drugs 34
    3.3 Experimental equipment installation 36
    3.4 Experimental Methods 39
    3.5 Analysis Method 42
    Chapter IV Results and Discussion 52
    4.1 Background Experiment 52
    4.1.1 Experiment 52 hydrogen peroxide
    4.1.2 Direct UV photolysis experiments 54
    4.1.3 ozonation experiments 59
    4.1.4 Summary 62
    4.2 with UV ozone / hydrogen peroxide degradation process alkylphenol compound 63
    4.2.1 Effect of initial pH of the solution 63
    4.2.2 Hydrogen peroxide dose 67
    4.2.3 The impact of ozone into the flow of the dose 73
    4.2.4 Effect of the initial concentration of the reactants 78
    4.3 the best combination of advanced oxidation process conditions of the study 81
    4.4 of alkyl phenol intermediates and degradation pathway inference 87
    4.5 of alkyl phenol and its intermediate products of biological toxicity study 97 with estrogenic activity
    Chapter V Conclusions and Recommendations 102
    5.1 Conclusion 102
    5.2 Recommendations 104
    References 105
    Appendix A-1 Reference 1.Adams, CD, PA Scanlan, and ND Secrist, "Oxidation and biodegradability enhancement of 1, 4-dioxane using hydrogen peroxide and ozone", Environmental Science & Technology, 28, pp. 1812-1818, (1994).
    2.Ahel, M., and W. Giger, "Aqueous solubility of alkylphenols and alkylphenol polyethoxylates", Chemosphere, 26, pp. 1461-1470, (1993).
    3.Alnaizy, R., and A. Akgerman, "Advanced oxidation of phenolic compounds", Advances in Environmental Research, 4, pp. 233-244, (2000).
    4.Arnold, SF, DM Klotz, BM Collins, PM Vonier, LJ Guillette Jr, and JA McLachlan, "Synergistic activation of estrogen receptor with combinations of environmental chemicals", Science, 272, pp. 1489-1492, (1996).
    5.Beltran, FJ, G. Ovejero, JF Garcia-Araya, and J. Rivas, "Oxidation of polynuclear aromatic hydrocarbons in water. 2. UV radiation and ozonation in the presence of UV radiation", Industrial & engineering chemistry research, 34 , pp. 1607-1615, (1995).
    6.Błędzka, D., D. Gryglik, and JS Miller, "Photolytic degradation of 4-tert-octylphenol in aqueous solution", Environment Protection Engineering, 35, pp. 235-247, (2009).
    7.Błędzka, D., D. Gryglik, M. Olak, J. Gębicki, and JS Miller, "Degradation of n-butylparaben and 4-tert-octylphenol in H2O2/UV system", Radiation Physics and Chemistry, 79, pp . 409-416, (2010).
    8.Cespedes, R., S. Lacorte, A. Ginebreda, and D. Barcelo, "Occurrence and fate of alkylphenols and alkylphenol ethoxylates in sewage treatment plants and impact on receiving waters along the Ter River (Catalonia, NE Spain)", Environmental Pollution, 153, pp. 384-392, (2008).
    9.Chang, BV, F. Chiang, and SY Yuan, "Anaerobic degradation of nonylphenol in sludge", Chemosphere, 59, pp. 1415-1420, (2005).
    10.Cheng, CY, CY Wu, CH Wang, and WH Ding, "Determination and distribution characteristics of degradation products of nonylphenol polyethoxylates in the rivers of Taiwan", Chemosphere, 65, pp. 2275-2281, (2006).
    11.Clara, M., S. Scharf, C. Scheffknecht, and O. Gans, "Occurrence of selected surfactants in untreated and treated sewage", Water Research, 41, pp. 4339-4348, (2007).
    12.Clarin, J., M. Fletcher, and D.Reichardt, (1998).
    ~ ceenve/enve/jsczechowski/enve436/projects/UV/UV-Ozone-Peroxide.html
    13.Corvini, PFX, A. Schaffer, and D. Schlosser, "Microbial degradation of nonylphenol and other alkylphenols - our evolving view", Applied Microbiology and Biotechnology, 72, pp. 223-243, (2006).
    14.Crittenden, JC, S. Hu, DW Hand, and SA Green, "A kinetic model for H2O2/UV process in a completely mixed batch reactor", Water Research, 33, pp. 2315-2328, (1999).
    15.Duong, CN, JS Ra, J. Cho, SD Kim, HK Choi, JH Park, KW Kim, and E. Inam, "Estrogenic chemicals and estrogenicity in river waters of South Korea and seven Asian countries", Chemosphere, 78 , pp. 286-93, (2010).
    16.Esplugas, S., J. Gimenez, S. Contreras, E. Pascual, and M. Rodriguez, "Comparison of different advanced oxidation processes for phenol degradation", Water Research, 36, pp. 1034-1042, (2002) .
    17.Flouriot, G., F. Pakdel, B. Ducouret, and Y. Valotaire, "Influence of xenobiotics on rainbow trout liver estrogen receptor and vitellogenin gene expression", Journal of molecular endocrinology, 15, pp. 143-151, ( 1995).
    18.Galindo, C., and A. Kalt, "UV/H2O2 oxidation of monoazo dyes in aqueous media: a kinetic study", Dyes and Pigments, 40, pp. 27-35, (1999).
    19.Glaze, WH, "Drinking-water treatment with ozone", Environmental Science & Technology, 21, pp. 224-230, (1987).
    20.Glaze, WH, JW Kang, and DH Chapin, "The chemistry of water treatment processes involving ozone, hydrogen peroxide and ultraviolet radiation", (1987).
    21.Hohne, C., and W. Puttmann, "Occurrence and temporal variations of the xenoestrogens bisphenol A, 4-tert-octylphenol, and tech. 4-nonylphenol in two German wastewater treatment plants", Environmental Science and Pollution Research, 15 , pp. 405-416, (2008).
    22.Hawrelak, M., E. Bennett, and C. Metcalfe, "The environmental fate of the primary degradation products of alkylphenol ethoxylate surfactants in recycled paper sludge", Chemosphere, 39, pp. 745-752, (1999).
    23.Hoigne, J., and H. Bader, "The role of hydroxyl radical reactions in ozonation processes in aqueous solutions", Water Research, 10, pp. 377-386, (1976).
    24.Hong, L., and MH Li, "Acute toxicity of 4-nonylphenol to aquatic invertebrates in Taiwan", Bull Environ Contam Toxicol, 78, pp. 445-9, (2007).
    25.Ince, NH, "" Critical "effect of hydrogen peroxide in photochemical dye degradation", Water Research, 33, pp. 1080-1084, (1999).
    26.Isobe, T., H. Nishiyama, A. Nakashima, and H. Takada, "Distribution and behavior of nonylphenol, octylphenol and nonylphenol monoethoxylate in okyo metropolitan area: Their association with aquatic particles and sedimentary distributions", Environmental Science & Technology , 35, pp. 1041-1049, (2001).
    27.Jeong, JJ, JH Kim, C. Kim, I. Hwang, and K. Lee, "3-and 4-alkylphenol degradation pathway in Pseudomonas sp. Strain KL28: genetic organization of the lap gene cluster and substrate specificities of phenol hydroxylase and catechol 2, 3-dioxygenase ", Microbiology, 149, pp. 3265-3277, (2003).
    28.Jie, X., W. Yang, Y. Jie, JH Hashim, XY Liu, QY Fan, and L. Yan, "Toxic effect of gestational exposure to nonylphenol on F1 male rats", Birth Defects Research Part B: Developmental and Reproductive Toxicology, 89, pp. 418-428, (2010).
    29.29.Korner, W., U. Bolz, W. Susmuth, G. Hiller, W. Schuller, V. Hanf, and H. Hagenmaier, "Input / output balance of estrogenic active compounds in a major municipal sewage plant in Germany" , Chemosphere, 40, pp. 1131-1142, (2000).
    30.Kim, SJ, SC Kim, SG Seo, DJ Lee, H. Lee, SH Park, and SC Jung, "Photocatalyzed destruction of organic dyes using microwave/UV/O3/H2O2/TiO2 oxidation system", Catalysis Today, 164 , pp. 384-390, (2011).
    31.Kuramitz, H., J. Saitoh, T. Hattori, and S. Tanaka, "Electrochemical removal of p-nonylphenol from dilute solutions using a carbon fiber anode", Water Research, 36, pp. 3323-3329, (2002 ).
    32.La Guardia, MJ, RC Hale, E. Harvey, and TM Mainor, "Alkylphenol Ethoxylate Degradation Products in Land-Applied Sewage Sludge (Biosolids)", Environmental Science & Technology, 35, pp. 4798-4804, (2001) .
    33.Langlais, B., DA Reckhow, and DR Brink, "Ozone in water treatment: Application and engineering: Cooperative research report", CRC, (1991).
    34.Lee, HB, and TE Peart, "Determination of 17 beta-estradiol and its metabolites in sewage effluent by solid-phase extraction and gas chromatography / mass spectrometry", Journal of AOAC international, 81, p. 1209, (1998) .
    35.Legrini, O., E. Oliveros, and A. Braun, "Photochemical processes for water treatment", Chemical Reviews, 93, pp. 671-698, (1993).
    36.Lopez, A., G. Ricco, G. Mascolo, G. Tiravanti, A. Di Pinto, and R. Passino, "Biodegradability enhancement of refractory pollutants by ozonation: a laboratory investigation on an azo-dyes intermediate", Water Science and Technology, 38, pp. 239-245, (1998).
    37.Lucas, MS, JA Peres, and GL Puma, "Treatment of winery wastewater by ozone-based advanced oxidation processes (O3, O3/UV and O3/UV/H2O2) in a pilot-scale bubble column reactor and process economics" , Separation and Purification Technology, 72, pp. 235-241, (2010).
    38.Mandavgane, SA, and MKN Yenkie, "Degradation of salicylic acid by UV, UV/H2O2, UV/O3, photofenton processes", (2011).
    39.Masten, SJ, and SHR Davies, "The use of ozonization to degrade organic contaminants in wastewaters", Environmental Science & Technology, 28, pp. 180-185, (1994).
    40.Mazellier, P., and J. Leverd, "Transformation of 4-tert-octylphenol by UV irradiation and by an H2O2/UV process in aqueous solution", Photochemical & Photobiological Sciences, 2, pp. 946-953, (2003 ).
    41.Mokrini, A., D. Ousse, and S. Esplugas, "Oxidation of aromatic compounds with UV radiation / ozone / hydrogen peroxide", Water Science and Technology, 35, pp. 95-102, (1997).
    42.Neamtu, M., and FH Frimmel, "Photodegradation of endocrine disrupting chemical nonylphenol by simulated solar UV-irradiation", Science of the Total Environment, 369, pp. 295-306, (2006).
    43.Neamtu, M., DM Popa, and FH Frimmel, "Simulated solar UV-irradiation of endocrine disrupting chemical octylphenol", J Hazard Mater, 164, pp. 1561-7, (2009).
    44.Nimrod, AC, and WH Benson, "Environmental Estrogenic Effects of Alkylphenol Ethoxylates", Critical Reviews in Toxicology, 26, pp. 335-364, (1996).
    45.Ning, B., NJ Graham, and Y. Zhang, "Degradation of octylphenol and nonylphenol by ozone - part II: indirect reaction", Chemosphere, 68, pp. 1173-9, (2007).
    46.Pothitou, P., and D. Voutsa, "Endocrine disrupting compounds in municipal and industrial wastewater treatment plants in Northern Greece", Chemosphere, 73, pp. 1716-1723, (2008).
    47.Ren, G., D. Sun, and JS Chunk, "Advanced treatment of oil recovery wastewater from polymer flooding by UV/H2O2/O3 and fine filtration", Journal of Environmental Sciences, 18, pp. 29-32, ( 2006).
    48.Rice, RG, "Applications of ozone for industrial wastewater treatment-a review", Ozone: science and engineering, 18, pp. 477-515, (1996).
    49.Routledge, EJ, and JP Sumpter, "Estrogenic activity of surfactants and some of their degradation products assessed using a recombinant yeast screen", Environmental Toxicology and Chemistry, 15, pp. 241-248, (1996).
    50.Sasai, R., D. Sugiyama, S. Takahashi, Z. Tong, T. Shichi, H. Itoh, and K. Takagi, "The removal and photodecomposition of n-nonylphenol using hydrophobic clay incorporated with copper-phthalocyanine in aqueous media ", Journal of Photochemistry and Photobiology A: Chemistry, 155, pp. 223-229, (2003).
    51.Sellers, RM, "Spectrophotometric determination of hydrogen peroxide using potassium titanium (IV) oxalate", The Analyst, 105, p. 950, (1980).
    52.Sonntag, C., P. Dowideit, X. Fang, R. Mertens, X. Pan, MN Schuchmann, and HP Schuchmann, "The fate of peroxyl radicals in aqueous solution", Water Science and Technology, 35, pp. 9-15 (1997).
    53.Soto, AM, H. Justicia, JW Wray, and C. Sonnenschein, "p-Nonyl-phenol: an estrogenic xenobiotic released from" modified "polystyrene", Environmental health perspectives, 92, p. 167, (1991).
    54.Staehelin, J., R. Buhler, and J. Hoigne, "Ozone decomposition in water studied by pulse radiolysis. 2. Hydroxyl and hydrogen tetroxide (HO4) as chain intermediates", The Journal of Physical Chemistry, 88, pp. 5999-6004, (1984).
    55.Staehelin, J., and J. Hoigne, "Decomposition of ozone in water: rate of initiation by hydroxide ions and hydrogen peroxide", Environmental Science & Technology, 16, pp. 676-681, (1982).
    56.Tanenbaum, DM, Y. Wang, SP Williams, and PB Sigler, "Crystallographic comparison of the estrogen and progesterone receptor's ligand binding domains", Proceedings of the National Academy of Sciences, 95, p. 5998, (1998).
    57.Trapido, M., J. Veressinina, and R. Munter, "Ozonation and AOP treatment of phenanthrene in aqueous solutions", Ozone: science & engineering, 16, pp. 475-485, (1994).
    58.Trapido, M., Y. Veressinina, and R. Munter, "Advanced oxidation processes for degradation of 2, 4-dichlo-and 2, 4-dimethylphenol", Journal of Environmental Engineering, 124, p. 690, (1998 ).
    59.Wu, J., J. Yang, M. Muruganandham, and C. Wu, "The oxidation study of 2-propanol using ozone-based advanced oxidation processes", Separation and Purification Technology, 62, pp. 39-46, (2008).
    60.Yao, JJ, ZH Huang, and SJ Masten, "The ozonation of pyrene: Pathway and product identification", Water Research, 32, pp. 3001-3012, (1998).
    61.Ying, GG, RS Kookana, A. Kumar, and M. Mortimer, "Occurrence and implications of estrogens and xenoestrogens in sewage effluents and receiving waters from South East Queensland", Science of the Total Environment, 407, pp. 5147 - 5155, (2009).
    62.Ying, GG, B. Williams, and R. Kookana, "Environmental fate of alkylphenols and alkylphenol ethoxylates - a review", Environment International, 28, pp. 215-226, (2002).
    63.Yu, Z., S. Peldszus, and PM Huck, "Adsorption characteristics of selected pharmaceuticals and an endocrine disrupting compound-Naproxen, carbamazepine and nonylphenol-on activated carbon", Water Research, 42, pp. 2873-2882, ( 2008).
    64.Zayas, PT, G. Geissler, and F. Hernandez, "Chemical oxygen demand reduction in coffee wastewater through chemical flocculation and advanced oxidation processes", Journal of Environmental Sciences-China, 19, pp. 300-305, (2007) .
    65.Zeff, JD, and E. Leitis, "Oxidation of organic compounds in water", US Patent, pp. 492-407, (1988).
    66.Zhang, YP, X. Zhou, YX Lin, and X. Zhang, "Ozonation of nonylphenol and octylphenol in water", Fresenius Environmental Bulletin, 17, pp. 760-766, (2008).
    67 Ding Wang Yin, Wu Yi, "environmental hormones - nonylphenol and bisphenol A in Taiwan aquatic environment analysis and spread Survey", environmental testing bimonthly, 33, pp.12-21, (2000).
    68 Cheng-Hsung Wang, Zhang Xiaoping, Li Yihua Huang Ren Gui, Sandy Chan, Wen-Tsung Hung, "Taiwan quasi environmental hormone substances management and environmental fate Survey", microbial and environmental hormones Symposium, (2000).
    69 Cheng-Hsung Wang, Zhang Xiaoping, Huang Ren block, Li Yihua, Wang Shiguan, Wen-Tsung Hung, 陈珮珊, "environmental hormones ─ nonylphenol residues investigate its effect on the physiological effects of male carp, " Taiwan Journal of Public Health, 20, pp.202 -215, (2001).
    70 Environmental Protection Administration, Chinese toxicological information processing libraries.
    71 Wuren Zhang, Lin Yifang, "the application of ozone concentration measured with" Measurement Information, page 62, pp.49-52, (1998).
    72 Wu Yanlin, Yu Yan, Yuan Haixia, DONG Wen-Bo, "aqueous UV-tert-octyl phenol degradation studies, " China Environmental Science, pp.1333-1337, (2010).
    73 Li Mei-hui, "common hormonal substances and their impact on the environment, " environmental hormones Symposium, Taipei, DCB, pp. 4-13, (2000).
    74 Linzi Yu, "nonylphenol human placental trophoblast cells induced oxidative damage and mitochondrial function impairment, " the Department of Medical Technology, Taipei Medical University, MA, Taipei, (2005).
    75. Linkun instrument, "in the ozone / UV processing environment hormonal substances - to bisphenol A, nonylphenol and octylphenol polyoxyethylene alcohol, for example, " Institute of Environmental Engineering, National Taiwan University, MA, Taipei , (2005).
    76 Kang Shifang, PC Chiang, Zhang Yiyi, Zhang Kan Kwok Ping, Li Jiawei, "drinking water and water quality standards in the tube material screening and monitoring program final report, " Environmental Protection Agency, Project No. EPA-98-U1J1-02 -101, (2009).
    77 Zhuang Xinyi, "Occupational Exposure Populations alkylphenols biological monitoring study, " Environmental Health Sciences, National Yang-Ming University, master's, New York, (2004).
    78 Chen Yi encyclical, "to H2O2/O3/UV procedures pesticide containing an aqueous solution of paraquat Study", Institute of Environmental Engineering, National Sun Yat-sen, MA, Kaohsiung, (2003).
    79 Chen Hsi-gold, "Surfactant Octylphenol Polyethoxylates biodegradable and restoration of research, " Institute of Environmental Engineering, National Central University, Ph.D., Taoyuan County, (2005).
    80. Huangrong Mao, Wang Yu Wen, Lin Shengfu, Yang Te-jen, "Encyclopedia of Chemistry", Xiaoyuan Press, (1987).
    81 Cai Weixin, "UV / hydrogen peroxide process degradation octylphenol polyoxyethylene alcohol aqueous solution of research, " Institute of Environmental Engineering, National Central University, MA, Taoyuan County, (2011).
    82 PC Chiang, Zhang Yiyi, Wang wealth, Wang root tree, "emerging contaminant monitoring, assessment, treatment and risk assessment of the research project final report, " Water Resources Agency, Project No. MOEAWRA0990016, (2010).
    83 Wei Japan, Lu Guiying, Liuguang Li, Jia Xiaoshan, "O3, UV, H2O2 and combinations Process comparative study of the effects of organic pollutants, " Environmental Engineering, 25, pp. 7-9, (2007).
    84 Gu Yang, "advanced oxidation process in wastewater treatment applications, " Industrial Pollution Prevention Technical Manual, 29, (1993). Advisor
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